Duphaston 10mg/Dydrogesterone -20 Tablets

Uses

Hormone replacement therapy

Duphaston is indicated to counteract the effects of unopposed oestrogen on the endometrium (inner lining of the uterus) in hormone replacement therapy for women with disorder due to naturally or surgically induced menopause with an intact uterus.

Progesterone deficiencies

Duphaston is indicated for the treatment of progesterone deficiencies such as treatment of:

•  Dysmenorrhea (painful menstruation)
•  Endometriosis (growth of uterine tissue outside the uterus with associated symptoms)
•  secondary amenorrhea (cessation of menstruation)
•  irregular cycles
• Dysfunctional uterine bleeding
• premenstrual syndrome
• Threatened and habitual abortion, associated with proven progesterone deficiency
• infertility due to luteal (ovarian yellow body) insufficiency
• Luteal support as part of an assisted (reproductive technology (ART) treatment

Dosage and administration

Always take Duphaston exactly as your Doctor has prescribed.

For hormone replacement therapy

In combination with continuous oestrogen therapy, take one tablet daily for 14 consecutive days of a 28-day cycle.

In combination with cyclical oestrogen therapy, take one tablets daily during the last 12 to 14 days of oestrogen therapy

For doctors: if endometrial biopsies or ultrasound reveal inadequate progestational response, 20 mg dydrogesterone should be prescribed.

Dysmenorrhoea (painful menstruation)

Take one tablet twice daily from day 5 to day 25 of the cycle

Endometriosis (abnormal growth of uterine tissues outside the uterus)

Take one tablet two or three times daily from day 5 to 25 of the cycle or continuously (as prescribed by your doctor

Dysfunctional bleeding (to prevent bleeding)

Take one tablet twice daily from day 11 to 25 of the cycle

Amenorrhoea (cessation of menstruation)

Your doctor should prescribe an oestrogen along with duphaston. Then take the oestrogen onc daily from day 1 to day 25 of the cycle, together with one tablet of dydrogesterone twice daily from day 11 to day 25 of the cycle.

Premenstrual syndrome

Take one tablet twice daily from day 11 to day 25 of the cycle

Irregular cycles

Take one tablet twice daily from day 11 to day 25 of the cycle

Threatened abortion

Take four tablets at once, then one tablet every eight hours until symptoms abate