Coveram 10mg/10mg(perindopril arginine/amlodipine) Tablets 30’s

Coveram 10mg/10mg is a combination medication containing perindopril arginine (10mg) and amlodipine (10mg). It is prescribed to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events in patients at high risk. This higher-dose combination is generally used for patients whose condition is not adequately controlled by lower doses or single-drug therapies.

Components and Their Functions

1. Perindopril Arginine (10mg)
   • Class: ACE inhibitor (Angiotensin-Converting Enzyme Inhibitor)
   • Function:
     • Relaxes blood vessels, lowering blood pressure.
     • Improves heart efficiency and reduces the risk of heart attacks and strokes.
     • Provides kidney protection in hypertensive patients with diabetes.
2. Amlodipine (10mg)
   • Class: Calcium channel blocker
   • Function:
     • Relaxes blood vessel walls to improve blood flow.
     • Reduces the workload on the heart.
     • Effectively manages angina (chest pain) and hypertension.

Uses of Coveram 10mg/10mg

• Hypertension: Helps achieve and maintain target blood pressure levels.
• Prevention of Cardiovascular Events: Reduces the risk of heart attacks, strokes, and other cardiovascular complications.
• Stable Coronary Artery Disease: Helps prevent complications associated with heart disease.

Dosage and Administration

• Dose: One tablet daily, as prescribed by your doctor.
• Time of Administration: Preferably taken in the morning at the same time each day.
• With or Without Food: Can be taken on an empty stomach or with meals.
• Do Not Split or Crush: Swallow the tablet whole.

Side Effects

Common Side Effects

• Perindopril-related:
  • Persistent dry cough
  • Dizziness or fainting (especially when standing up quickly)
  • Fatigue
• Amlodipine-related:
  • Swelling in the ankles or feet (edema)
  • Flushing or warmth in the face
  • Headache

Rare but Serious Side Effects

• Severe allergic reactions (swelling of the face, lips, or tongue)
• Irregular heartbeat or worsening chest pain
• Liver problems (dark urine, yellowing of the skin or eyes)