Trental (Pentoxifylline) 400mg Modified release -90 Tablets

Trental or pentoxifylline, is a prescription medication widely used to improve blood circulation. It belongs to a class of drugs called xanthine derivatives and is primarily prescribed for conditions caused by poor blood flow, especially in the legs.

Pentoxifylline works by making red blood cells more flexible and reducing blood thickness. This allows blood to flow more easily through narrowed or damaged blood vessels, improving oxygen delivery to tissues.

What Is Trental (Pentoxifylline) Used For?

Doctors commonly prescribe Trental to treat intermittent claudication associated with peripheral arterial disease (PAD).

People with this condition frequently experience leg pain, cramping, or fatigue while walking due to reduced blood flow.

Other uses of pentoxifylline include:

• Improving circulation in patients with diabetes-related vascular complications

• Supporting treatment in chronic venous insufficiency

• Enhancing blood flow in certain cerebrovascular disorders

How Pentoxifylline Works in the Body

Pentoxifylline improves blood flow by:

• Increasing red blood cell flexibility

• Decreasing blood viscosity (thickness)

• Reducing platelet aggregation

• Enhancing oxygen delivery to tissues

These effects collectively help reduce pain, numbness, and discomfort caused by restricted circulation.

Trental Dosage and How to Take It

Take Trental 400 mg two to three times daily, preferably with meals, to minimize stomach upset. Swallow the tablets whole and do not crush or chew them.

Dosage may vary depending on the patient’s condition, age, and kidney or liver function. Always follow your Doctors or healthcare professional instructions.

Possible Side Effects of Trental

Common side effects include:

• Nausea or vomiting

• Dizziness or headache

• Flushing

• Stomach discomfort

Rare but serious side effects may include chest pain, irregular heartbeat, or bleeding. Seek medical attention if unusual symptoms occur.

Precautions and Warnings

Use Trental cautiously in patients with:

• Bleeding disorders

• Recent stroke or heart attack

• Severe kidney or liver disease

Pregnant or breastfeeding women should consult a Doctor  before using pentoxifylline.